CRISPR/Cas9 engineering of albino cystinuria Type A mice

the investigation of the relationship between type a and type b personalities and quality of translation

چکیده ندارد.

A mouse model for cystinuria type I.

Cystinuria, one of the most common inborn errors of metabolism in humans, accounts for 1-2% of all cases of renal lithiasis. It is caused by defects in the heterodimeric transporter system rBAT/b0,+AT, which lead to reduced reabsorption of cystine and dibasic amino acids through the epithelial cells of the renal tubules and the intestine. In an N-ethyl-N-nitrosourea mutagenesis screen for reces...

An Animal Model of Type A Cystinuria Due to Spontaneous Mutation in 129S2/SvPasCrl Mice

Cystinuria is an autosomal recessive disease caused by the mutation of either SLC3A1 gene encoding for rBAT (type A cystinuria) or SLC7A9 gene encoding for b0,+AT (type B cystinuria). Here, we evidenced in a commonly used congenic 129S2/SvPasCrl mouse substrain a dramatically high frequency of kidney stones that were similar to those of patients with cystinuria. Most of 129S2/SvPasCrl exhibited...

The chromatographie studies of a case of cystinuria in Iran

Effects of Benzene on Kidney Structure in Mice (Albino Nmri)

Purpose: Study of benzene effects on kidney structure in mammals (mouse). Materials and Methods: The mice were studied in 3 groups: controls, solvent and treatment, at favorable laboratory conditions. Treatment mice were administered orally of benzene (0.1cc of benzene solution) for 10 days at a dose 1000 mg/kg of body weight. At the end of each period, the kidneys separated and fixed in paraf...